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- To: MLUG Off-Topic Discussion <EMAIL:PROTECTED>
- Subject: Re: [MLUG - DISCUSSION] [Politics] Amendment 2 ads and lies
- From: Stephen Montgomery-Smith <EMAIL:PROTECTED>
- Date: Wed, 01 Nov 2006 09:18:54 -0600
- Delivery-date: Wed, 01 Nov 2006 09:19:17 -0600
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- Organization: University of Missouri
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Hargus, Diana wrote:
Stephen Montgomery-Smith wrote:
Sent: Tuesday, October 31, 2006 3:11 PM
To: MLUG Off-Topic Discussion
Subject: Re: [MLUG - DISCUSSION] [Politics] Amendment 2 ads and lies
Hargus, Diana wrote:
Stephen Montgomery-Smith wrote:
2. Embryonic stem cell research is a more complicated issue to me.
Nevertheless, I am sufficiently convinced that the ethical
issues are
troublesome that I personally will vote against supporting
it. As far
as I understand, the nucleus of the embryo is replaced by a nucleus
from the recipient. This new embryo is them allowed to grow
until it
is producing stem cells. I see it as a distinct possibility
that this
new cell complex (the embryo with the new nucleus) is now a
new living
human being, and so to grow it to a certain number of days and then
stop it growing is a form of murder. Certainly whether this is done
in the womb or not is irrelevant as far as I can see. (I
think Mike's
use of the word "womb" from Psalm 139 is a misapplication.)
Perhaps this would be so in the case of cloning, but embryonic stem
cell research involves removing a cell from the blastocyst at the
pluripotent
(sp?) stage. Otherwise pretty close.
Hi Diana - can you explain what this means? I am getting the
sense that you truly know what is involved in this kind of
research, and that you may be able to answer questions which
were unanswered on this group a year ago.
Thanks, Stephen
Stephen,
Thank you for thinking that I may know more than I do, but I have found
in life I have a lot to learn. In the case of cloning, the process is
as you described in the first part (as I understand current techniques).
"As far as I understand, the nucleus of the embryo is replaced by a
nucleus from the recipient. This new embryo is them allowed to grow
until it is producing stem cells"
In most, but not all, stem cell research, it is also done this way as
well with a donor supplying the cellular material. In the case of the
totipotent (total potential, i.e. able to take on all cellular roles or
ability to form a viable embryo) stem cell, I would like to find out
more as well, but find there is too little time to research it properly.
In the case of the pluripotent (potential to become any part of the
whole, able to differentiate, but not able to grow into a whole embryo)
stem cell, it is usually taken from the blastocyst after the totipotent
stage. There are 3 main parts of the blastocyst - called the mesoderm,
ectoderm, and endoderm (I think that was what they were).
It is after this stage in embryonic development where the cells become
multipotent (potential limited to small number of specialized cell types
and are responsible for cellular replacement capabilities in organs -
skin and kidneys are good examples, although that is just off the top of
my head) and become too differentiated to be effective for their
intended use in research. These are also adult stem cells I believe,
and there a multitudinal variety of them.
As to the exact science involved, I have not a clue. All I know is
theory and very little of that. Note that I know very little and am no
expert, but love reading and trying to figure things out. I am
currently working (trying?) on a patent application for future desktop
interfaces and my mind is shot, so take what I say with a grain of salt.
If there is an error, I would like to know so that I can research it and
correct it.
Sorry I could not give a better answer.
Diana
My understanding is this. An embryo starts to grow. If it is being
used for research (that is one of the "stem cell lines") I don't think
that the nucleus is replaced. If it is to be used therapeutically, I
think that the nucleus does need to be replaced, and this with that of
the recipient. My understanding is that this second stage has not been
performed successfully, but that a South Korean scientist had made this
claim fraudulently.
Now presumably at different stages in its growth, different parts of the
embryo are harvested. The cell tissue, once harvested, presumably is
not a human being, and so the ethical issues involved are equivalent to
handling finger nail clippings. But there still remains the issue of
what happens to the original embryo. At some point, after being
reawakened from its frozen slumber, it is then killed.
Now all of this does require that we have some understanding of when the
embryo truly acquires personhood. Traditional ideas are things like
viability, or when it develops a nervous system. But personally I think
it takes place a lot earlier, and involves some kind of life being
breathed into it by God in a way that is currently totally beyond the
understanding of science.
As I have said, given the consequences if it is unethical, I myself will
vote that we do not fund more of this research, until we can be
absolutely certain that this research is completely ethical.
Stephen
--
Stephen Montgomery-Smith
EMAIL:PROTECTED
http://www.math.missouri.edu/~stephen
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